What is the normal range for antiphospholipid syndrome?

The reference range findings are as follows: Less than 15 immunoglobulin G (IgG) phospholipids units (GPL): Absent or none detected. Less than 12 immunoglobulin M (IgM) phospholipids units (MPL): Absent or none detected. Less than 12 immunoglobulin A (IgA) phospholipids units (APL): Absent or none detected.

What is normal range for cardiolipin?

Reference range: IgG anticardiolipin: Weak positive: 15-40U/ml. Positive: >40U/ml.

What does high cardiolipin IgG mean?

The levels of these antibodies are often high in people with abnormal blood clotting, autoimmune diseases like systemic lupus erythematosus (SLE), or repeated miscarriages.

What is cardiolipin AB IgA IgG IgM?

The cardiolipin antibodies blood test, IgA, IgG, and IgM is used to help investigate inappropriate blood clot formation, to help determine the cause of recurrent miscarriage, or as part of an evaluation for antiphospholipid syndrome or sometimes other autoimmune diseases.

How long can you live with antiphospholipid syndrome?

Results: Thirty-eight patients (15%) died during the follow-up period. Mean age of the decreased was 35.4 +/- 12.2 years (range 21-52 years) and the disease duration 8.6 +/- 8.2 years (range 0.6-20), the median length of the survival from the time of the diagnosis was 6.2 +/- 4.3 years.

When should you suspect antiphospholipid syndrome?

A diagnosis of APS can usually be confirmed if you have had: 1 or more confirmed blood clots. 1 or more unexplained late miscarriages at or after week 10 of your pregnancy. 1 or more premature births at or before week 34 of your pregnancy.

What is a normal cardiolipin antibody IgM?

Ref range previously listed as: IgG: 0-14 (Negative), 15-19 (Indeterminate), 20-80 (Low to Medium Positive), 81 or higher (High Positive), IgM: 0-12 (Negative), 13-19 (Indeterminate), 20-80 (Low to Medium Positive), 81 or higher (High Positive) 3/3/2017: Updated reference range with new testing kit.

What is high Anticardiolipin AB IgM QN?

High levels of the IgM isotype are associated with autoimmune hemolytic anemia, a condition in which an individual’s immune system attacks their red blood cells.

What does the high IgM titer indicate?

High levels of IgM can mean macroglobulinemia, early viral hepatitis, mononucleosis, rheumatoid arthritis, kidney damage (nephrotic syndrome), or a parasite infection is present.

What does a high Anticardiolipin AB IgM QN mean?

– Moderately or very high levels of anticardiolipin antibodies that persist for 12 weeks or more indicate a continued presence of these autoantibodies and an increased risk of abnormal clots and miscarriages.

What does a negative cardiolipin mean?

A negative result means only that cardiolipin antibodies are not present or not present at a detectable level in the blood at the time of the test. Cardiolipin antibodies are the most common of the antiphospholipid antibodies.

What is the IgM code for cardiolipin IgG?

1 Test Name: CARDIOLIPIN (IGG, IGM) ANTIBODIES. 2 Lab Order Codes: CARL. 3 Synonyms: Phospholipid Antibodies (Cardiolipin Antibodies) IgG and IgM, Serum; 4 Anti-Phospholipid Antibodies; Anticardiolipin Antibodies; Phosolipid Ab. 5 (Cardiolipin) IgG and IgM, Serum. 6 (more items)

What are the different types of anticardiolipin antibodies?

There are three types of anticardiolipin antibodies: IgG, IgA and IgM. The test measures IgG and IgM levels. A negative anticardiolipin IgG or IgM result indicates that this type of antibody was not present or was present in too small a quantity in the blood sample being tested.

What is the Iga cardiolipin antibody test?

For pregnant women who are affected by APS, the test is used to monitor the conditions of pregnancy to prevent risks. In general, the IgG and IgM tests are conducted first. If these tests are negative but clinical suspicions still exist, then the IgA cardiolipin antibody testing may be ordered.

What is the significance of IgG and IgM CL levels in APS?

Lower positive levels of IgG and/or IgM CL antibodies (above cutoff but less than 40 GPL and/or less than 40 MPL units) may occur in patients with the clinical symptoms of APS; therefore, the actual significance of these levels is undefined.