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The Daily Insight

What are the side effects of Zometa?

Author

Caleb Butler

Updated on April 02, 2026

Common side effects of Zometa include:

  • dizziness,
  • headache, or.
  • flu-like symptoms (such as fever, chills, muscle/joint aches),
  • cough,
  • vision problems,
  • diarrhea,
  • constipation,
  • tired feeling,

What is the most common side effect of zoledronic acid?

Fever is the most common adverse effect associated with zoledronic acid infusion. Flu-like syndromes including fever, chills, bone pain, and/or arthralgias and myalgias have also occasionally been reported.

What are the side effects of zoledronic acid?

More common

  • Abdominal or stomach pain.
  • back pain.
  • bad, unusual, or unpleasant (after) taste.
  • bladder pain.
  • blistering, crusting, irritation, itching, or reddening of the skin.
  • bone pain.
  • burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings.
  • change in taste.

What is the most common side effect of bisphosphonate?

The most common side effect of bisphosphonate medications is stomach upset. The medication can cause inflammation of the esophagus and even lead to erosions of the surface of the esophagus.

What does Zometa do to your body?

Zoledronic acid belongs to a class of drugs known as bisphosphonates. It lowers high blood calcium levels by reducing the amount of calcium released from your bones into your blood. It also works by slowing the breakdown of your bones by cancer to prevent bone fractures.

Does zoledronic acid cause weight gain?

Tell your doctor if you have serious side effects of Reclast including urinating less than usual or not at all; drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting, swelling, weight gain, shortness of breath, muscle spasms, numbness or tingling (especially around your mouth).

Are bisphosphonates bad for teeth?

The most common complication in patients on bisphosphonate therapy is osteonecrosis of jaw (ONJ) which can occur after any surgical dental procedure and the risk for the development of osteonecrosis of jaw is higher in patients receiving intravenous bisphosphonate therapy than in patients receiving oral bisphosphonate …

Why are bisphosphonates bad for you?

Bisphosphonates can cause problems with the jaw or thigh bone. But most women do not have these side effects. They seem to be more likely if women take bisphosphonates for more than 5 years. Whether you take medicine or not, healthy habits can help protect your bones.

What can I expect from Zometa infusion?

Dizziness, headache, tiredness, or flu-like symptoms (such as fever, chills, muscle/joint aches) may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

How does Zometa affect your teeth?

If you are having dental procedures while receiving this medicine, you may have an increased chance of having a severe problem with your jaw. Make sure you tell your doctor or dentist about any new problems, such as pain or swelling, with your teeth or jaw.

What are the most common side effects of Zometa?

Common Zometa side effects may include: anemia. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect Zometa?

Is zoledronic acid the same as Zometa?

Zoledronic acid (Zometa) Zoledronic acid is a type of drug known as a bisphosphonate. It has the brand name Zometa. It reduces the risk of fractures in cancers that affect the bones, such as: It also lowers high levels of calcium in the blood (hypercalcaemia), which can happen in secondary bone cancer.

How long does it take for Zometa to wear off?

This usually takes a few days to a couple of weeks. However, some rare but serious side effects, such as damage to the jawbone or thigh fractures, can take several weeks or longer to improve. If you have severe bone, muscle, or joint pain from Zometa, this should improve after you stop treatment.

How is Zometa administered for hypercalcemia?

Zometa is administered under physician supervision. The maximum recommended dose of Zometa in hypercalcemia of malignancy or in patients with multiple myelomaand metastatic bone lesions from solid tumors is 4 mg as a single-dose intravenous infusion over no less than 15 minutes. Duration of treatment varies depending on the condition being treated.