Is polycystic kidney disease serious?
Sarah Martinez
Updated on April 03, 2026
Polycystic kidney disease can also cause cysts to develop in your liver and elsewhere in your body. The disease can cause serious complications, including high blood pressure and kidney failure. PKD varies greatly in its severity, and some complications are preventable.
What is the life expectancy of polycystic kidney disease?
Autosomal dominant polycystic kidney disease is a genetic disorder affecting 1 in 1000 people worldwide and is associated with an increased risk of intracranial aneurysms. The average life expectancy of a patient with ADPCKD ranges from 53 to 70 years, depending on the subtype.
Is polycystic kidney curable?
There’s currently no cure for autosomal dominant polycystic kidney disease (ADPKD), and it’s not possible to stop cysts forming in the kidneys. But there are some potentially useful medications, such as tolvaptan, that can sometimes be used to reduce the growth rate of cysts.
What causes PKD cysts to grow?
Cysts (pronounced sists) are sacs of fluid. In people with PKD, many cysts grow inside of their kidneys, making the kidneys much larger than they should be. The cysts caused by PKD grow from the tiny filters in the kidneys, called nephrons. People with PKD can have thousands of cysts in their kidneys at once.
Can PKD cysts be removed?
Laparoscopy and cyst removal is the treatment of choice for most patients with numerous or very large cysts. The laparoscopic approach is best for removing a large number of cysts and for those with a condition called adult polycystic kidney disease (APCKD).
Can you drink alcohol with polycystic kidney disease?
Drinking alcohol can generally be done safely in moderation, even if you have CKD, polycystic kidney disease, end stage renal disease (ESRD) or diabetes. Take caution, however, if you have high blood pressure.
What is polycystic kidney disease (PKD)?
Polycystic kidney disease (PKD or PCKD, also known as polycystic kidney syndrome) is a genetic disorder in which the renal tubules become structurally abnormal, resulting in the development and growth of multiple cysts within the kidney. These cysts may begin to develop in utero, in infancy, in childhood, or in adulthood.
Where can I find information on polycystic kidney disease?
Genetics Home Reference (GHR) contains information on Polycystic kidney disease. This website is maintained by the National Library of Medicine. The National Kidney and Urologic Diseases Information Clearinghouse (NIDDK) conducts and supports research on a broad spectrum of diseases affecting public health.
Is polycystic kidney disease dominant or recessive?
Most cases of polycystic kidney disease have an autosomal dominant pattern of inheritance. People with this condition are born with one mutated copy of the PKD1 or PKD2 gene in each cell. In about 90 percent of these cases, an affected person inherits the mutation from one affected parent.
Can a PKD cyst change the shape of your kidneys?
Unlike the usually harmless simple kidney cysts that can form in the kidneys later in life, PKD cysts can change the shape of your kidneys, including making them much larger. PKD is a form of chronic kidney disease (CKD) that reduces kidney function and may lead to kidney failure.